New rabies virus discovered in Tanzania
A new type of rabies virus has been discovered in Tanzania by scientists from the University of Glasgow and the Animal Health and Veterinary Laboratories Agency (AHVLA).
Scientists believe the new virus is likely to originate in bats and that cross-over infection to civets and other mammalian species is likely to be relatively rare. However further studies are planned to determine the extent of infection and the degree of risk to human and animal health.
Professor Sarah Cleaveland, of the Institute of Biodiversity, Animal Health and Comparative Medicine at the University of Glasgow, said: “The vast majority of human deaths from rabies are caused by bites from domestic dogs with rabies, which can be effectively controlled through mass dog vaccination campaigns.
“This new virus is unlikely to pose a threat to humans on the scale of that of dog rabies. However this research highlights the need for vigilance and maintaining good levels of surveillance.
“The study also demonstrates how powerful new genetic tools are revealing the complexity of emerging viruses at the wildlife –human interface.”
"Due to the highly divergent nature of this novel virus it is not clear whether current human and animal vaccines will confer protective immunity and are effective following an exposure."
The discovery of rabies in the civet following the attack on the child in the Ikoma ward of the Serengeti on 11 May 2009 was highly unexpected as the Serengeti National Park has been free of rabies since 2000 as a result of domestic dog vaccination campaigns around the park. The characterisation of the virus in this study indicates that this new case did not result from a breach in the dog vaccination barrier, but from a new source of infection.
The discovery is reported in a paper entitled ‘Ikoma Lyssavirus, Highly Divergent Novel Lyssavirus in an African Civet’, in the journal Emerging Infectious Diseases.
The research was supported by The Department for Environment, Food and Rural Affairs, the EU FP7-funded Research Infrastructure Grant European Virus Archive, the Research and Policy for Infectious Disease Dynamics program of the Science and Technology Directorate (US Department of Homeland Security), and the Fogarty International Center. In Tanzania the work was funded by Lincoln Park Zoo (Chicago, USA), the Wellcome Trust, UBS Optimus Foundation and the Medical Research Council.
For more information contact Stuart Forsyth in the University of Glasgow Media Relations Office on 0141 330 4831 or email stuart.forsyth@glasgow.ac.uk
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